The Red Sea receives abundant dust supply from dust storms originated in the Sahara and Arabian Peninsula regions. The Red Sea acts as a sink for this dust, which also acts as a vehicle for microbes. Airborne microbes have been recognized as a poorly characterized component of the biosphere and, although their load is low, the transport rates, fluxes and distances can be phenomenal. This research will develop, using metagenomic approaches, a first description of the airborne microbial communities over the Red Sea, their sources and their role upon entering the Red Sea. As well as, exposing different groups of marine organisms to biotic and abiotic stressors in order to measure their stress related genes expression as a response to various levels of warming, dust, plastic, UV and hypoxia.