Hologenome analysis of two marine sponges with different microbiomes

T. Ryu, L. Seridi, L. Moitinho-Silva, M. Oates, Y.J. Liew, C. Mavromatis, X. Wang, A. Haywood, F.F. Lafi, M. Kupresanin, R. Sougrat, M.A. Alzahrani, E. Giles, Y. Ghosheh, C. Schunter, S. Baumgarten, M.L. Berumen, X. Gao, M. Aranda, S. Foret, J. Gough, C.R
BMC Genomics, volume 17, article number 158, (2016)

Hologenome analysis of two marine sponges with different microbiomes

Keywords

Sponge, Stylissa carteri, Xestospongia testudinaria, Innate immune system, Host , Microbial symbionts, Hologenome

Abstract

Background

Sponges (Porifera) harbor distinct microbial consortia within their mesohyl interior. We herein analysed the hologenomes of Stylissa carteri and Xestospongia testudinaria, which notably differ in their microbiome content.

Results

Our analysis revealed that S. carteri has an expanded repertoire of immunological domains, specifically Scavenger Receptor Cysteine-Rich (SRCR)-like domains, compared to X. testudinaria. On the microbial side, metatranscriptome analyses revealed an overrepresentation of potential symbiosis-related domains in X. testudinaria.

Conclusions

Our findings provide genomic insights into the molecular mechanisms underlying host-symbiont coevolution and may serve as a roadmap for future hologenome analyses.

Code

DOI: 10.1186/s12864-016-2501-0

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